Affiliation

Martin Omondi

Research Scientist

omondim@kipre.go.ke

Qualifications

Ongoing PhD: Medical Microbiology
University of Nairobi

Projects

Drug repurposing for malaria treatment
January 2026 – Present · Ongoing
January 2024 - Mechanisms underlying Schistosoma egg extravasation
July 2024 - Platform for rapid immunological characterization of SARS-CoV-2 variants in Kenya and the Eastern Africa Region (PRICOS study)
Leishmaniasis Survey study in West Pokot
April 2024
Steroids for pneumonia trial (SONIA) study
2022-2023
Expanding diagnostic capacity of COVID-19 and understanding the role of immunity in disease progression in Kenya
2021-2022
A preclinical animal model for evaluating the efficacy of nano-formulated antimalarial drugs during pregnancy
2019 – Present · Ongoing
Amboseli Baboon Project PBMC isolation and characterization
June 2022
Covid-19 sample collection and processing
2020-2021
A portable multiplexing electrochemical metalo-immunosensor array for detection of Schistosoma cercarial antigens in polluted waters
2020-2021
Screening for Karposi sarcoma-like virus in non-human primates
2019-2020
In Vitro Anti-Plasmodial Activity of the Crude Extracts of Phyllanthus Sepialis and Rumex Steudelii
2019-2020
Antimalarial Activity of Leaves, Roots, Fruit, and Stem Extracts of Thelgate (Aristolochia Bracteolata Lam) Plant Against In Vivo and In Vitro Plasmodium Falciparum Infections
2019-2020
Amboseli Baboon Project PBMC isolation and immune characterization
2019

Publications

1.Waweru, G., Nyakundi, R., Kutima, B., Owuor, S., Konyino, G., Gitonga, J., Lugano, D., Maina, A., Musyoki, J., Ochola, L., Omondi, M., Kariuki, C. K., Ogongo, P., Mwachari, C., Shee, F., Agoti, C., Sande, C., Uyoga, S., Kagucia, E., ... Nyagwange, J. (2025). Assessing the Impact of SARS-CoV-2 Spike Mutations on Antibody Binding: A Comparative Assessment of the Wuhan and JN.1 Variants’ Full-Length Spikes in a Multiplex Luminex Assay. Viruses, 17(9), 1248. https://doi.org/10.3390/v17091248View →
2.Linda Obiero, Edinah Songoro, Martin Omondi, Ruth Nyakundi, and Lucy Ochola. Human Papillomavirus Vaccine immune responses in an olive baboon model is not compromised by chronic Schistosoma mansoni infections [J]. AIMS Microbiology, 2025, 11(3): 720-736. doi: 10.3934/microbiol. 2025030View →
3.Nyirenda M, Kanoi BN, Martin Omondi, Steven Ger Nyanjom. Lucy Ochola. Evaluating the potential of Schistosoma mansoni Soluble Egg Antigen (SEA) and Glycoproteins (IPSE and Omega-1) in Inhibiting the Progression of Type 1 Diabetes [version 1; peer review: awaiting peer review]. F1000Research 2025, 14:576 (https://doi.org/10.12688/f1000research.165548.1)View →
4.Alfred MO, Ochola L, Okeyo K, Bae E, Ogongo P, Odongo D, Njaanake K and Robinson JP (2025) Application of microphysiological systems to unravel the mechanisms of schistosomiasis egg extravasation. Front. Cell. Infect. Microbiol. 15:1521265. doi: 10.3389/fcimb.2025.1521265View →
5.Ochola, L., Gitaka, J., Kanoi, B., Kimani, C. N., Akala, H. M., Alfred, M. O., Ochola‐Oyier, L. I., & Ogutu, B. (2025). Malaria Chemotherapeutics: What Next for Africa? Advanced Therapeutics, 8(4). https://doi.org/10.1002/adtp.202400453View →
6.Yu, L.; Li, L.; Liu, J.; Sun, H.; Li, X.; Xiao, H.; Alfred, M.O.; Wang, M.; Wu, X.; Gao, Y.; et al. Recombinant Reg3α Prevents Islet β-Cell Apoptosis and Promotes β-Cell Regeneration. Int. J. Mol. Sci. 2022, 23, 10584. https://doi.org/10.3390/ijms231810584View →
7.Anderson, J. A., Lea, A. J., Voyles, T. N., Akinyi, M. Y., Nyakundi, R., Ochola, L., Omondi, M., Nyundo, F., Zhang, Y., Campos, F. A., Alberts, S. C., Archie, E. A., & Tung, J. (2022). Distinct gene regulatory signatures of dominance rank and social bond strength in wild baboons. Philosophical Transactions of the Royal Society B: Biological Sciences, 377(1845). https://doi.org/10.1098/rstb.2020.0441View →
8.Hai-na Zhang, Ying Dai, Chun-hong Zhang, Alfred Martin Omondi, Arunima Ghosh, Ipsita Khanra, Manas Chakraborty, Xu-ben Yu, Jing Liang. Sirtuins family as a target in endothelial cell dysfunction: implications for vascular aging. April 2020. https://doi.org/10.1007/s10522-020-09873-zView →
9.Hai-na Zhang, Qiao-qiao Xu, Abhimanyu Thakur, Martin Omondi Alfred, Manas Chakraborty, Arunima Ghosh, Xu-ben Yu, Endothelial dysfunction in diabetes and hypertension: Role of microRNAs and long non-coding RNAs. Life Sciences Journal. DOI: 10.1016/j.lfs.2018.10.028. 2018View →
10.Chen Luo, Lu-TingYu, Meng-QiYang, Xiang Li, Zhi-Yuan Zhang, Martin Alfred, Jun-Li Liu, Min Wang. Recombinant Reg3β protein protects against streptozotocin-induced β-cell damage and diabetes. Scientific reports. 2016, DOI: 10.1038/srep35640View →
11.Yu Lu-Ting; Meng-Qi Yang; Jun-Li Liu; Martin Omondi Alfred; Xiang Li; Xue-Qing Zhang; Juan Zhang; Ming-Yuan Wu; Min Wang; Chen Luo. Recombinant Reg3alpha protein protects against experimental acute pancreatitis in mice. Molecular and Cellular Endocrinology Journal. 2016, 422:150-159