Faith Photo Faith Onditi

Faith I. Onditi

Senior Research Scientist

faith@kipre.go.ke

Qualifications

  • PhD

    University of Nairobi (UoN) · 2015

Projects

  • Development of Silk Fibroin Haemostatic Gauze for Rapid Bleeding Control: Alternative to Conventional Gauze

  • AI-Enabled Research Infrastructure at KIPRE- Embracing Agentic AI to Digitalize Preclinical and Human Sample Research

  • In vitro and in vivo propagation of Plasmodium knowlesi in Papio Anubis (Olive baboons)

  • Liver and blood stage infection of Aotus griseimembra with aseptic, purified, cryopreserved Plasmodium falciparum (NF54 strain) sporozoites.

  • Aotus nancymaae as a Novel Non-human Primate Model of Chronic Placental Malaria.

  • Liver and blood stage infection of Saimiri boliviensis and Saimiri sciureus by inoculation of purified, cryopreserved Sanaria® Plasmodium vivax sporozoite (PfSPZ)

  • Developed a cell-free biosensor project targeting harmful water pathogens and chemical pollutants (E. coli, Lead, Fluoride) without needing a standard lab

  • The baboon (Papio anubis)-Plasmodium knowlesi model for placental malaria

  • Congenital Malaria and Maternal Protection in Baboons," focusing on critical aspects of malaria transmission and immunity

  • Pathology of Placental Malaria in Baboons (Papio anubis) infected with Plasmodium knowlesi

  • The Distribution of Spiroplasma in Danaus chrysippus (butterfly) from Ngong Hills, Kenya

Publications

  1. 1.Mogaka S., Onditi F., Ogila K., Higashi C., Ozwara H. Antimalarial drug discovery and development: Assay system challenges and the translational relevance of Plasmodium knowlesi–baboon model.J Adv Biotechnol Exp Ther. 2026 Jan; 9(1): 52-66.
  2. 2.Mogaka S, Mulei I., Njoki P., Ogila K., Waihenya R., Onditi F., Ozwara H. Antimalarial Efficacy and Safety of Senna occidentalis (L.) Link Root Extract in Plasmodium berghei-Infected BALB/c Mice. Biomedical Research International. Biomed Research International (2023), vol. 2023, article ID 8296195.
  3. 3.Mogaka S., Molu S., Kagasi E., Ogila K., Waihenya R., Onditi F., Ozwara H. Senna occidentalis (L.) Link root extract inhibits Plasmodium growth in vitro and in mice. BMC Complementary Medicine and Therapies (2023), 71 (2023).
  4. 4.Nyirongo J., Onditi F., Simbauni J., Kamau L., Mwangi V., Kagasi E., Ozwara H. Astemizole-Methylene Blue combination therapy reduces monotherapy adverse effects in Balb/C mice. Journal of Pharmaceutical Research International (2022) 34(53A):42-52
  5. 5.Nyirongo J., Kamau L., Simbauni J., Mwangi V., Kagasi E., Onditi F., Ozwara H. Drug Recovery: Effect of Astemizole-Methylene Blue combination therapy against Plasmodium strains in Vitro, South Asian Journal of Parasitology (2020) 4(3):9-17
  6. 6.Taylor E., Onditi F., Maina N., Ozwara H. Immunization of mice with soluble lysate of interferon-gamma expressing Plasmodium berghei ANKA induces high IFN-γ production. Tropical Diseases, Travel Medicine and Vaccines (2017) 3:11
  7. 7.Mogaka S., Muriithi C., Onditi, F.I., Mumo R, Maina, N, Waihenya R., Ozwara, H.S. Plasmodium berghei is immunomodulated by transgenic mouse interferon-gamma leading to enhanced malaria protection in mice, Journal of Pharmacy and Biological Sciences,2015
  8. 8.Onditi, F.I., Nyamongo, W.O., Omwandho, C., Maina, N., Maloba, F., Farah, I.O., King, C., Moore, J., Ozwara, H.S. Parasite accumulation in placenta of non-immune baboons during Plasmodium knowlesi infection. Malaria Journal (2015) 14:118. Published Conference Abstracts: 1. Onditi F., Howard Jen., Nadakal S., Torano Holly., Doritchamou J., Spiegel ., Stevens R., Morrison R., Neal J., Raitin J., Bock K., Ouahes T., Orr-Gonzalez S., Alves D., Lambert L., Fried M., Duffy P: Aotus nancymaae as a Novel Non-human Primate Model of Chronic Placental Malaria. NIAID 18th Annual Fellows Workshop, 2024 2. Onditi F., Renn., Lambert L., Ouahes T., Orr-Gonzalez S., Neal J., Alani N., Doritchamou J., Fried M., Duffy P: Impact of in utero malaria exposure on susceptibility of Aotus nancymaae offspring to Plasmodium falciparum parasitemia during early years of life. American Society of Tropical Medicine & Hygiene, 2024 Annual Meeting 3. Onditi F., Lambert L., Ouahes T., OrrGonzalez S., Neal J., Chakravarty S., James E., Sim K., Stephen L. Hoffman S., Duffy P. First liver and blood stage infection of Saimiri boliviensis and Saimiri sciureus by inoculation of purified, cryopreserved Sanaria® Plasmodium vivax Sporozoite (PfSPZ), American Society of Tropical Medicine & Hygiene, 2023 Annual Meeting 4. Onditi F., Howard J., Nadakal S., Torano H., Doritchamou J., Spiegel A., Morrison B., Neal J., Raitin J., Ouahes T, OrrGonzalez S., Lambert L., Fried M., Duffy P. Aotus nancymaae as a novel non-human primate model of chronic placental malaria. 9th Future of Malaria Research Symposium abstract book, 2023, pg. 10 5. Oduor J., Onkoba N., Maloba F, Arodi O., Nyachieo A., Onditi F. Safety and therapeutic efficacy of Staphylococcus aureus specific lytic phage against multidrug-resistant S. aureus (MDRSA) in BALB/c mice: A prospective study. International Journal of Infectious Diseases (2016) 45:108 6. Onditi F., Omwandho C., Ozwara H. The baboon (Papio anubis)-Plasmodium knowlesi model of placental malaria. International Journal of Infectious Diseases (2016) 45:62 7. Onditi F., Omwandho C., Maloba F., Christopher K., Moore M., Hastings Ozwara H, In Utero Sensitization of Plasmodium knowlesi in baboon infants., 2014, URI: http://repository.kyuc.ac.ke/123456789/166 8. Onditi F., Onkoba N., Omwandho C., Ozwara H, Moore J., Baboon (Papio anubis) as a potential model for understanding immunological mechanism of placental malaria, 2012. URI: http://repository.kyuc.ac.ke/123456789/168View →
  9. 9.Onditi F., Onkoba N., Omwandho C., Ozwara H., Moore J., Baboon (Papio anubis) as a model for developing future diagnostic tools for placental malaria in humans, 2012.URI: http://repository.kyuc.ac.ke/123456789/167View →
  10. 10.Onditi F., Onkoba N., Omwandho C., Maina N., Maloba F, Farah O., King C., Moore J., Ozwara H., Placental malaria pathology and fetal outcomes in baboon (Papio anubis) infected with Plasmodium knowlesi H strain, 2010. URI: http://hdl.handle.net/123456789/99.View →